![]() Enterotoxins found in bacteria and plants act mainly as pore-forming toxins and toxic lectins, respectively. Many of these are enterotoxins, leading us to explore this activity in PV2. This binary structure resembles AB-toxins, a group of toxins otherwise restricted to bacteria and plants. In this regard, Pomacea snail eggs, in addition to immune defenses, have evolved the perivitellin-2 or PV2 combining two immune proteins into a neurotoxin: a lectin and a pore-forming protein from the Membrane Attack Complex/Perforin (MACPF) family. Gastropod Molluscs rely exclusively on the innate immune system to protect from pathogens, defending their embryos through maternally transferred effectors. Epstein, Cátedra de Patología General Veterinaria, Universidad Nacional de La Plata (UNLP), La Plata, Argentina
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